Compliance Issues

Medications don't work if patients don't take them...

DoseCue Circuitry

Yet 80% of patients do not follow their physician's dosing instructions.1

Patient noncompliance is an ongoing medical issue that presents serious consequences and significant costs to patients, the healthcare industry, and our society.

  • The #1 problem in treating illness today is patient failure to take medicine correctly, regardless of age2

  • Non-compliant patients experience disease complication, untoward side effects, and require emergency treatment3,4

  • Estimated total annual cost of medical non-adherence is $300 billion5

  • Median compliance rate across therapeutic area, gender, age, and ethnicity is estimated at 50%6

  • Hospital costs due to patient non-compliance are estimated at $8.5 billion annually

  • The cost of drug-related morbidity and mortality exceeded $177 billion nationwide in 20007

  • Compliance drops 50% within 10 months of patient starting chronic medication(s) using traditional commercial pharmaceutical packaging



References: 1. Healthcare Compliance Packing Council & Task Force for Compliance Report. 1993. 2. American Heart Association. Statistics you need to know: statistics on medication. Available at: http://www.americanheart.org/presenter.jhtml?identifier=107. Accessed October 25, 2009. 3. Dunbar-Jacob J, Schlenk EA. Treatment adherence and clinical outcome: can we make a difference? In: Resnick RJ, Rozensky RH, eds. Health Psychology Through the Life Span: Practice and Research Opportunities. Washington, DC: American Psychological Association; 1996:323—343.  4. Col N, Fanale JE, Kronholm P. The role of medication noncompliance and adverse drug reactions in hospitalizations of the elderly. Arch Intern Med. 1990;150:841—845. 5. DiMatteo MR. Variations in patients’ adherence to medical recommendations: a quantitative review of 50 years of research. Med Care. 2004;42:200—209. 6. Dunbar-Jacob J, Erlen JA, Schlenk EA, et al. Adherence in chronic disease. In: Fitzpatrick JJ, Goeppinger J, eds. Annual Review of Nursing Research. Vol. 18. New York, NY: Springer Publishing Co.; 2000:48—90. 7. Ernst FR, Grizzle AJ. Drug-related morbidity and mortality: updating the cost-of-illness model. J Am Pharm Assoc. 2001;41:192—199.



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NOTE: Avarvistar and Sextant Pharmaceuticals are ficticious names for demonstration only.
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